In this work, a current-mode instrumentation amplifier with common-mode current cancellation is realized using enhanced CCII topology. Detailed CMRR analysis is performed and parameters for maximizing the CMRR are defined. The proposed structure is simulated using SPICE and realized on a prototyping board. According to the simulation and measurement results the proposed circuit shows superior CMRR performance compared to other well- known current-mode instrument amplifier topologies.